Hand, foot, and mouth disease (HFMD) is a contagious illness caused by enteroviruses, commonly seen in children. Its primary symptoms include fever, oral ulcers, and hand and foot blisters.
The issue of whether soaking lychees in chemical solutions can lead to HFMD has been surrounded by numerous controversies and misconceptions. This article will delve into this topic in detail, analyzing it from multiple perspectives to reveal the truth.
I. Basic Understanding of Hand, Foot, and Mouth Disease
Hand, foot, and mouth disease, also known as pediatric HFMD or vesicular stomatitis with exanthema, is an acute contagious illness primarily caused by enteroviruses such as Coxsackievirus and Enterovirus 71.
Its transmission routes mainly include the digestive tract, respiratory droplets, and close contact. Patients usually have a history of contact with infected individuals within one to two weeks before the onset of illness, such as contact with the patient’s secretions, feces, or contaminated items.
The symptoms of HFMD typically include fever, oral ulcers, and hand and foot blisters. Oral ulcers may manifest as pain, refusal to eat, drooling, etc.
Hand and foot blisters mostly appear on the palms, soles, and buttocks, usually as maculopapules or vesicles. In rare cases, severe complications such as aseptic meningitis, encephalitis, acute flaccid paralysis, neurogenic pulmonary edema, and myocarditis may occur.
II. The Actual Situation of Soaking Lychees in Chemical Solutions
Lychee is a fruit rich in sugar and vitamins, deeply loved by people for its delicious taste and abundant nutritional value.
However, there are indeed some challenges in the preservation and transportation of lychees, such as their susceptibility to rot and insects. Therefore, some merchants may adopt the method of soaking lychees in chemical solutions to extend their shelf life.
The process of soaking lychees in chemical solutions usually involves the use of chemical reagents such as antimicrobials and preservatives. These reagents include imazalil, prochloraz, tebuconazole, and thiabendazole. They are not highly toxic and have strict usage limits.
When used reasonably and in compliance with standards, these reagents generally do not pose a hazard to humans. However, excessive use or the use of unsafe chemical reagents may adversely affect human health.
In addition, there is a rumor about soaking lychees in chemical solutions that involves the use of “formalin,” a weakly corrosive chemical solution. However, formalin is primarily used for preserving specimens and disinfection, and it is not suitable for the preservation of lychees. Therefore, this rumor is likely a misunderstanding or myth.
III. The Relationship Between Soaking Lychees in Chemical Solutions and Hand, Foot, and Mouth Disease
Whether soaking lychees in chemical solutions can lead to HFMD is a complex issue. Based on current scientific research and clinical data, soaking lychees in chemical solutions does not directly cause HFMD.
HFMD is a contagious illness caused by enteroviruses, and its transmission routes and pathogenesis are not directly related to soaking lychees in chemical solutions.
However, during the process of soaking lychees in chemical solutions, if unsterilized utensils are used or the water source is contaminated, there may be a certain infection risk.
Additionally, lychees are rich in sugar, providing a favorable growth environment for viruses, which may increase the risk of HFMD infection to some extent. It should be noted that this risk is not directly caused by soaking lychees in chemical solutions but rather arises from improper handling or hygiene issues during the process.
Furthermore, some susceptible populations, such as children or individuals with weakened immune systems, may have an increased likelihood of contracting HFMD after contact with lychees.
This is mainly because their immune systems are relatively weaker and more susceptible to viral attacks. However, this does not mean that soaking lychees in chemical solutions directly causes HFMD but rather reflects different reactions due to individual differences and immune status.
IV. Similarities Between Lychee Allergy and HFMD Symptoms

It is worth noting that lychee allergy can also cause some symptoms similar to HFMD. The symptoms of lychee allergy include oral swelling, skin rashes, itchiness, respiratory distress, and digestive symptoms.
These symptoms have some similarities with some symptoms of HFMD (such as oral ulcers and hand and foot blisters), which may lead to misdiagnosis or confusion.
Lychee allergy occurs when the body’s immune system overreacts to lychee proteins, causing mast cells to release inflammatory mediators such as histamine, triggering local tissue edema and inflammation.
In contrast, HFMD is a contagious illness caused by enteroviruses, and its pathogenesis is completely different from allergic reactions. Therefore, it is essential to differentiate between the two diseases during diagnosis to avoid misdiagnosis.
V. Measures to Prevent Hand, Foot, and Mouth Disease
The key to preventing HFMD is to maintain good personal hygiene habits and strengthen self-protection awareness. Here are some effective preventive measures:
- Wash hands frequently: Wash hands promptly before eating, after using the toilet, and after returning home from outside, using soap and running water to reduce virus residue on the hands.
- Avoid contact with patients: Try to avoid close contact with patients, especially their secretions, feces, or contaminated items.
- Pay attention to environmental hygiene: Keep the living environment clean and dry, and regularly disinfect daily items, toys, and utensils.
- Improve immunity: Maintain a balanced diet, engage in moderate exercise, ensure sufficient sleep, etc., to improve the body’s immunity and reduce the likelihood of viral infection.
- Vaccination: For susceptible populations such as children, they can receive the HFMD vaccine to prevent the occurrence of the disease.
VI. Correct Consumption Methods of Lychees
To avoid potential health risks associated with lychees, consumers need to pay attention to the following points when purchasing and consuming them:
- Choose fresh lychees: When purchasing lychees, choose those with a reddish color, full fruit, and no signs of spoilage.
- Thoroughly wash lychees: Before consumption, soak lychees in a diluted saltwater solution with baking soda for 15 minutes to thoroughly wash off pesticide residues and dirt on the surface.
- Consume lychees in moderation: Lychees are rich in sugar, and excessive consumption may lead to symptoms such as heatiness and oral ulcers. Therefore, it is recommended to consume them in moderation and not eat too many at once.
- Pay attention to oral hygiene: Brush your teeth and rinse your mouth promptly after eating lychees to prevent the sugar in lychees from remaining in the oral cavity, which may cause dental caries and gum swelling and pain.
VII. Conclusion
In summary, soaking lychees in chemical solutions does not directly cause HFMD. HFMD is a contagious illness caused by enteroviruses, and its transmission routes and pathogenesis are not directly related to soaking lychees in chemical solutions.
However, improper handling or hygiene issues during the process of soaking lychees in chemical solutions may increase the risk of HFMD infection. Additionally, lychee allergy may cause some symptoms similar to HFMD, but their pathogenesis is completely different.
To prevent health risks such as HFMD and lychee allergy, consumers need to pay attention to choosing fresh lychees, thoroughly washing them, consuming them in moderation, and maintaining oral hygiene when purchasing and consuming them. At the same time, maintaining good personal hygiene habits and strengthening self-protection awareness are also key measures to prevent HFMD.
In conclusion, lychee is a nutritious fruit that is beneficial to the body when consumed in moderation. However, safety and hygiene issues need to be considered during consumption to avoid potential health risks.
The prevention of contagious illnesses such as HFMD should rely on scientific methods and measures rather than blindly believing rumors or misconceptions.